This portal provides gene expression, eQTL, and sQTL data for multiple rat tissues. It is managed by the NIDA Center of Excellence for Genetics, Genomics, and Epigenetics of Substance Use Disorders in Outbred Rats (P30DA060810).
The raw data for the tissues in this portal come from multiple studies. The processed data, however, may differ from the results reported in each study for a couple reasons:
Tissue | Abbreviation | Samples (rn6) | Samples (rn7) | Originating study |
---|---|---|---|---|
Infralimbic cortex | IL | 81 | 83 | P50 DA037844 Y1-5, Project 2 |
Lateral habenula | LHb | 81 | 82 | P50 DA037844 Y1-5, Project 2 |
Nucleus accumbens core | NAcc | 75 | 77 | P50 DA037844 Y1-5, Project 2 |
Orbitofrontal cortex | OFC | 80 | 82 | P50 DA037844 Y1-5, Project 2 |
Prelimbic cortex | PL | 80 | 82 | P50 DA037844 Y1-5, Project 2 |
Eye | Eye | 51 | 53 | R01 EY021200 |
Basolateral amygdala | BLA | 185 | 191 | U01DA046077 |
Nucleus accumbens core | NAcc2 | 188 | 193 | U01DA046077 |
Prelimbic cortex | PL2 | 191 | 194 | U01DA046077 |
Adipose | Adipose | 411 | 411 | R01DK106386 |
Liver | Liver | 401 | 411 | R01DK106386 |
Brain hemisphere | Brain | 339 | 340 | Pilot: Creating the dataset for TWAS in HS rats |
For the tissues above whose originating study has been published (see below), you may use the data in your studies by citing the originating study. For the other tissues, contact us about whether, when, and how you may use them.
More info on the ratgenes.org eQTL page. Additional publications will be posted when available.
Tissues from the same study are from the same set of rats, though the final subsets per tissue differ slightly after quality control filtering. See the sample info page for details.
Also try searching for a gene in the toolbar to view its expression and eQTLs.
For questions or comments related to the data or website, email Daniel Munro at dmunro@health.ucsd.edu.
RatGTEx is primarily developed in the labs of Abraham Palmer at UC San Diego and Pejman Mohammadi at Seattle Children's Research Institute and University of Washington.
RatGTEx is produced by the NIDA Center of Excellence for Genetics, Genomics, and Epigenetics of Substance Use Disorders in Outbred Rats (P30DA060810). It is not a project of the GTEx Consortium.
Code for visualizations was adapted from the GTEx portal viz tools, and additional design considerations were inspired by the GTEx portal.
See also PhenoGen Informatics, the site for quantitative genetics of the transcriptome.